Her doctor had her on Claritin-D 24 Hour but then told her that would affect her because her family has a history of high blood pressure. She then placed her on Flonase. She may want to give plain Claritin (the antihistamine component of the drug) a try, as antihistamines in general pose no problem for those at risk for high blood pressure. There is no ready explanation as to why Flonase seemed to cause panic attacks and heart palpitations. Doctors give trusted answers on uses, effects, side-effects, and cautions: Dr. Turck on does flonase raise blood pressure: Antihistamine shouldn't raise blood pressure. Doctors give trusted answers on uses, effects, side-effects, and cautions: Dr. Turck on does flonase raise blood pressure: Antihistamine shouldn't raise blood pressure. Flonase: Fluticasone propionate belongs to the class of medications called corticosteroids. It is used to treat seasonal allergic rhinitis, including hay fever, and perennial rhinitis. It can be used to manage symptoms such as sinus pain and pressure associated with allergic rhinitis. It may take 2 to 3 days for the medication to reach its full. Symptoms of Cushing syndrome include fatigue, high blood sugar levels, high blood pressure and anxiety. Adrenal suppression refers to a decrease in adrenaline hormones and may lead to weight loss, low sugar levels (hypoglycemia), nausea and vomiting. Along with its needed effects, fluticasone nasal (the active ingredient contained in Flonase) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. However, in instances, where an underlying cause for the condition cannot be determined, high blood pressure is referred to as essential hypertension and where a direct cause for high blood pressure is established, the condition is known as secondary hypertension. While over the counter medications are not off limits to those with high blood pressure, nasal decongestants and other cold remedies can be cause for concern if you have high blood pressure. Is still at 100 more I am on high blood pressure. Medication. So my blood pressure. Is under. Control but heart rate. Is still at 100the or higher all the time why? Medication. So my blood pressure. The manufacturer's product labeling should always be consulted for a list of side effects most frequently appearing in patients during clinical studies.